Here is the synopsis for the Grimm season premiere:
After their face-off with Kimura (guest star Brian Tee), Nick (David Giuntoli) finds himself trying to come to grips with the return of his mother, Kelly Burkhardt (guest star Mary Elizabeth Mastrantonio). A trail of brutal murders unveils a foreign conspiracy to hunt down Nick, leading to several revelations about his past. Meanwhile, Juliette (Bitsie Tulloch) still lies in her mysteriously-induced coma as Rosalee (Bree Turner) and Monroe (Silas Weir Mitchell) work tirelessly to bring her out of it safely.Mike Dopud will make an appearance in next week's episode, and John Pyper-Ferguson guest stars in episode 2x03.
Elsewhere, Hank (Russell Hornsby) struggles with the shocking truths he’s recently seen and Captain Renard (Sasha Roiz) deals with unexpected family issues when his estranged brother (guest star James Frain) comes back into his life. Reggie Lee also stars.
Grimm will air Mondays at 10 until Friday, September 14, when it moves back to its old slot, Fridays at 9. Collider has a pretty good overview of things to look forward to this season. Here is a preview with the cast: